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Research

Wentian Yang, MD, PhD ($40,000)
“Protein Tyrosine Phosphatase Shp2 in Osteoclastogenesis and Bone Remodeling

Presentations:
3/6/2010 - New Orleans the 56th annual ORS Meeting .  Podium Presentation “Osteoclast Development and Skeletal Remodeling Require PTPase Shp2

3/25/2010 - Institute of Molecular Medicine, Peking  University , Beijing  “ Regulation of PI3 Kinase Pathway by Rsk2-Mediated Negative Feedback Signaling”

3/24/2010 - Institute of Basic Medical Science, Peking Union Hospital/Chinese Academy of Medical Science   “Shp2 Mutations in Myeloid Proliferative Disorders”

2/6/2010 - Boston Biology and Biotechnology Conference, Brandies University, Boston/MA. Podium Presentation  “Regulation of c-Fms Signaling and Osteoclast Development by Shp2”

Papers:
Wentian Yang, Caterina Iorio, Gordon Chan, Sunao Takeshita, Sumin Kang,  Jing Chen, Jack Taunton, Peter J. Quesenberry, Benjamin G. Neel.   A Rsk2-Mediated Negative Feedback Loop Regulates M-CSF-Evoked PI-3 Kinase/Akt Activation   Science (Signaling), 2010 (under review)

Grant:
NIHR21AR057156 Yang (PI) 10/09-9/11
“Shp2 in Osteoclastogenesis and Bone Remodeling”
The major goal of this project is to understand the biological and biochemical role of Shp2 in osteoclast development and function.

See Also

Annual Meeting

Annual Meeting Location May 16-19, 2012 in Denver, CO

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